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M9490469.TXT
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1994-09-19
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Document 0469
DOCN M9490469
TI Inhibitors of HIV-1 transcription.
DT 9411
AU Li CJ; Dezube BJ; Biswas DK; Ahlers CM; Pardee AB; Divn of Cell Growth
and Regulation, Dana-Farber Cancer Institute,; Boston, MA 02115.
SO Trends Microbiol. 1994 May;2(5):164-9. Unique Identifier : AIDSLINE
MED/94332441
AB No curative drug against HIV has yet been found, despite enormous
efforts aimed at reverse transcriptase and a variety of other targets.
The long terminal repeat (LTR) of HIV-1 has recently become a promising
site for antiviral action. This article briefly summarizes information
on the nature of this target and potential anti-LTR expression drugs.
DE Acquired Immunodeficiency Syndrome/*DRUG THERAPY Antiviral
Agents/*PHARMACOLOGY/THERAPEUTIC USE Base Sequence Human HIV Long
Terminal Repeat/*GENETICS HIV-1/*DRUG EFFECTS/GENETICS Models,
Biological Molecular Sequence Data Support, Non-U.S. Gov't Support,
U.S. Gov't, P.H.S. Trans-Activation (Genetics)/DRUG EFFECTS
Transcription, Genetic/*DRUG EFFECTS JOURNAL ARTICLE REVIEW REVIEW,
TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).